Mibolerone is a potent oral steroid derived from nandrolone. This drug is 7.17 dimethylated nandrolone, which is more potent than nandrolone. Mibolerone has maintained a reputation as one of the most powerful steroids in the world. In standard animal testing, mibolerone showed 41 times greater anabolic activity than methyltestosterone. Androgenic activity was 18 times higher. Estrogenic and progestogenic side effects are also evident. It is usually used by athletes in mass-building courses and to stimulate aggression before training or competition.
Miboleron was described in 1963. He got into veterinary medicine during the 1960s. It has not been used in animals for more than 24 consecutive months due to the risk of serious complications. Mibolerone is still available in the United States, but only under a veterinary license.
Mibolerone is not available as a prescription drug. When it was released, it was in the form of a propylene glycol solution, and contained 100mcg of steroid per milliliter in a 55ml vial.
Mibolerone is a modified nandrolone. It differs in:
- the addition of a methyl group at the 17alpha position, which protects the drug when taken orally,
- the addition of a methyl group at the 7alpha position, which inhibits 5-alpha reductase and increases the resistance to binding to binding globulin and increases biological activity.
Estrogenic side effects:
Mibolerone aromatizes and is considered a highly estrogenic steroid due to its conversion to 7,17-dimethylestradiol. Gynecomastia may be troubling, especially with high doses. Water retention can also become a problem, muscle appearance is lost and fat storage increases.
To avoid severe estrogenic side effects, it may be necessary to use an anti-estrogen such as tamoxifen. Aromatase inhibitors such as arimidex can be used alternately, which more effectively controls estrogen levels. However, aromatase inhibitors can be more expensive and can have a negative effect on blood lipids. Mibolerone has an affinity for progesterone receptors. This can cause progesterone side effects such as an interruption in testosterone production and an increase in body fat.
Progestins also increase the stimulating effect of estrogen on breast tissue growth. There is such a strong interaction that gynecomastia can be caused by progestins alone, without increasing estrogen levels. The use of anti-estrogens can alleviate gynecomastia caused by progestogenic AAS.
Androgenic side effects:
Mibolerone is classified as an anabolic, but androgenic side effects are very possible. This can be increased oily skin, acne, hair growth on the body and face. Anabolic steroids can worsen male-pattern hair loss. Sensitive people may substitute nandrolone decanoate for it.
Women additionally need to be aware of the potential virilizing effects of AAS. This may include a hardened voice, irregular periods, changes in skin texture, facial hair growth, and an enlarged clitoris. Mibolerone does not react with 5a-reductase due to its 7-alpha methylation, and its androgenicity cannot be altered by concurrent administration of finasteride or dutasteride.
Side effects (hepatotoxicity):
Mibolerone is a c17-alpha alkylated drug. This change protects the drug from liver deactivation, allowing a larger percentage of the drug to enter the bloodstream after oral administration. Alkylated AAS can be hepatotoxic. Long-term use or high doses can damage the liver. In rare cases, life-threatening dysfunction can develop. It is advisable to visit a doctor periodically during the course to monitor liver function. Alkylated AAS consumption is usually limited to 6-8 weeks to avoid increased liver stress. This makes it very toxic to the liver.
Side effects (cardiovascular system):
AAS can have harmful effects on blood cholesterol. This may be a decrease in the level of “good” HDL, a shift in the balance towards the risk of atherosclerosis. The relative effect of AAS on lipids depends on dose, route of administration, type of steroid and level of resistance to hepatic metabolism. Mibolerone has a stronger negative effect on hepatic cholesterol management due to its non-aromatizing structure and route of administration.
- AAS can have a negative effect on blood pressure and triglycerides,
- reduce vascular endothelial relaxation,
- provoke ventricular hypertrophy, which potentially increases the risk of cardiovascular disease and heart attack.
To reduce the stress on the cardiovascular system, it is recommended to minimize the consumption of saturated fat, cholesterol and simple carbohydrates during the course of the AAS. The use of supplements such as fish oil, lipid stable or similar products is recommended.
Suppression of testosterone:
All AAS, in doses required for muscle building, suppress endogenous testosterone production. Without the intervention of substances stimulating the production of testosterone, testosterone will return to normal levels within 1-4 months after the course. Note that with prolonged hypogonadotropic hypogonadism may develop into secondary hypogonadism and require medical attention.
Studies have shown that taking oral AAS with food decreases the bioavailability of the drug. This is due to the fat-soluble nature of the AAS, which may allow some of the drug to dissolve in the fat from food, which will reduce the absorption of the AAS in the gastrointestinal tract. For maximum effect, this drug must be taken on an empty stomach.
Reception (for men):
An effective dosage for improving physique or increasing physical performance is in the range of 500 mcg (5 ml) per day or less. Some people can take 1mg a day, although this level is fraught with side effects. You can buy Miboleron (Cheque Drops) by following the link https://anabolicmenu.ws/products/global-anabolic-cheque-drops-500/.
Mibolerone is not sold in pharmacies. He may be caught on the black market.